Orion’s post doc programme combines academic research and corporate resources to promote health

Julia Lindqvist and Henrik Paavilainen, who both joined Orion following their postdoctoral research period, want to highlight the fact that lowering boundaries between academia and the corporate world is a win-win for all. Among other things, it helps to develop new drugs more quickly than before.

Julia Lindqvist, Ph.D. in Cell/Cellular and Molecular Biology, started as a postdoctoral researcher at Orion in 2017, soon after completing her doctorate.

“My dissertation was related to oncology research. I had been wanting to work for a pharmaceutical company for a long time and to see how the research findings in my field could be put into practice,” she says.

Lindqvist drew up her research plan in collaboration with Orion.

“I set out to investigate how a molecule developed by Orion affects breast cancer cells and how the efficacy of the treatment can be improved by combining different medications.”

New research methods, new therapies

Henrik Paavilainen, Ph.D. in Virology, started his post doc period shortly after Lindqvist. Encouraged by Orion researcher Ari-Pekka Koivisto, Paavilainen took a leap into the unknown, and entered a field he was not previously familiar with.

“I studied the way in which a new method could be used in drug development. In the new method, stem cells are differentiated into nerve cells, which makes it possible to study pain. This area had not been previously investigated in this way at Orion.”

During the postdoctoral research period, he was able to determine the possibilities and limitations of the method.

“We also discovered completely new paths, and things that would be worth a closer look.”

Building a career at Orion

Both postdoctoral researchers joined Orion as permanent employees following their post doc period. Lindqvist has continued her work on oncology research:

“My job involves assessing new drug targets and configuring cellular models and methods around new ideas. Our Head of Oncology Research is Anu Moilanen, who was also my supervisor during my post doc period,” she says.

Paavilainen works in Orion’s New Therapies unit.

“I research how, for example, gene therapy or cell therapy could be used in new drug development, particularly in therapies for cancer and rare central nervous system diseases.”

PoDoCo programme helps Orion recruit post docs each year

Both Lindqvist and Paavilainen first joined Orion as postdoctoral researchers through the DIMECC PoDoCo programme. Orion recruits 1–2 postdoctoral researchers through the programme each year.

DIMECC Oy is a Finnish innovation platform that brings together industrial and research knowhow. When a new postdoctoral researcher receives funding through the PoDoCo programme, for a year for example, the host company agrees to fund a second period of the same length. The postdoctoral researcher will work at the company based on their own research plan.

Orion was recently awarded the annual DIMECC Prize for its contribution to the PoDoCo programme.

Cooperation that benefits everyone

Orion is an active member of the research community otherwise and provides resources for the supervision of dissertations.

“I have already supervised one master’s thesis while I have been at Orion, and at the moment I’m supervising a doctoral student,” Paavilainen says.

Orion also collaborates closely with several universities and researcher networks in drug development.

“Everyone benefits when the boundaries between academia and the corporate world are as low as possible. It means that new drugs can be developed much quicker,” Paavilainen says.

He emphasises that there is no competition between the corporate and the academic spheres and that the two only support each other.

Patient’s best interest at heart

Both postdoctoral researchers are very happy with their career choices.

Paavilainen says it has been great to see how everyone in drug development works towards a common goal.

“I can easily ask for advice from colleagues if I’m faced with a new method or instrument that I’m not yet familiar with. Orion has experts in so many different fields. Of course, the resources in the private corporate sector are different from those in the public sector,” he adds.

“But everyone shares the same goal: to bring a new drug to the market to promote patients’ well-being,” Lindqvist emphasises.

Drug development is not a sprint

Drug development is a very long-term commitment. Projects typically last several years. Only a few of the drug candidates finally lead to a pharmaceutical product.

According to Lindqvist, every day along the journey is rewarding.

“I learn something new every day. I have the privilege of fully utilising my researcher skills, to solve various problems – obviously as a member of a team – and to decide in which direction we should move next. The work of a researcher is incredibly fascinating!” she concludes.

 

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